Marking the 50th anniversary of one among this philosopher's most distinguished pieces, Blumenberg's Rhetoric proffers a decidedly dialogic and diversified interaction with the essay polyvalently entitled 'Anthropological Approach to the Actuality and Topicality (or Currency, Relevance) of Rhetoric' (Anthropologische Annäherung an die Aktualität der Rhetorik), first published in 1971. Following Blumenberg's lead, the contributors consider and tackle their topics rhetorically, 'in utramque partem vel in plures'--treating (inter alia) the variegated discourses of Phenomenology, the History of Philosophy, Anthropology, and the téchne (...) itself from a plurality of viewpoints. Quasi in actu--as a mise en abyme of this rhetorical method par excellence--said accent on approaching any matter polyperspectivally is reflected in the proceedings of the live(ly) discussions having taken place in preparation for the present volume. Along with the diachronically extensive, disciplinarily diverse essays, this publication of the actual academic interplay--notably in the current lingua franca--will facilitate, and is to conduce to, further scholarship with respect to Blumenberg and the art of rhetoric. (shrink)

Amyotrophic lateral sclerosis (ALS) is a progressive degenerative disorder of motor neurones. Although the genetic basis of familial forms of ALS has been well explored, the molecular basis of sporadic ALS is less well understood. Recent evidence has linked sporadic ALS with the failure to edit key residues in ionotropic glutamate receptors, resulting in excessive influx of calcium ions into motor neurones which in turn triggers cell death. Here we suggest that edited AMPA glutamate (GluR2) receptor subunits serve as gatekeepers (...) for motor neurone survival. BioEssays 30:1185–1192, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

This paper is an interpretation and defense of Putnam’s claim that reductionist sentences identifying experiences with physical events or processes are meaningless. Discourses are formulated within frameworks that are characterized by their methods of justification, types of term introduction, and vocabularies. Examples of both meaningful intra-framework and meaningless cross-framework identities are considered, along with examples of theoretical identities across sub-frameworks. In agreement with Putnam, mental/physical identities are classified as cross-framework. But I qualify Putnam’s thesis by arguing that they can be (...) meaningful to theextent they provide guides to beneficial social actions.’. (shrink)

The later MSS. of the Metamorphoses of Apuleius have received little attention. Hildebrand's edition, the last to give an extensive apparatus criticus, appeared in 1842, and seven years later Keil announced his belief that all the MSS. which he had seen in Italy were derived from Laur. 68. 2 , the famous eleventh century MS., written at Monte Cassino, and now at Florence. Since Keil, all texts have been based almost exclusively on F, with assistance from its twelfth or thirteenth (...) century copy Laur. 29. 2 , in the enormous number of places where F is now illegible. (shrink)

In my previous article I argued that certain of the later MSS. of the Metamorphoses of Apuleius, and especially those which I call Class I., are to a large extent descended from a lost copy of F, made before the rent was torn in Book VIII., and therefore before the writing of ; and I inferred that it was likely that the evidence of these MSS. would prove a valuable addition to that of in places where F is now illegible. (...) In the following pages I shall prove that this hope has been fulfilled. (shrink)

The manuscripts of Cicero's De oratore divide into two families: mutili and integri. The oldest representatives of the mutilated family are Avranches 238 , Erlangen 380 , and London, Harley 2736 . A and H are independent of each other, and the best witnesses to the text of the lost archetype . E too is considered to be an independent witness. Since the work of E. Ströbel, dating from the early eighties of the last century, the view has been generally (...) held that E, though closely related to A, is not a descendant of it but a copy of a ‘gemellus’ of A. The stemma devised by Ströbel has remained essentially the same to the present day. (shrink)

The possible role of the neurotransmitter serotonin in human affiliative behavior is under-examined in the review by Depue & Morrone-Strupinsky (D&M-S). This commentary reviews evidence indicating that serotonin not only inhibits aggressive behavior that may be detrimental to affiliative bonds with others in a social group but serotonin also enhances prosocial behaviors that may facilitate ties to the social group.

In two recent papers Joseph Margolis has sketched a situation, his characterisation of which involves a denial of the ubiquitous contention that knowing that p is logically sufficient for believing that p. There are not many philosophers who would follow him in this denial of what is most usually taken as the only “natural” way of construing knowledge. If Margolis has not succeeded in constructing a counterexample to the official view, and I do not believe that he has, it is (...) of some importance to understand just why he has failed. No epistemological gain is achieved by meeting Margolis with a question begging reply, as I think has been done by his critic, J.A. Barker.The case the Margolis offers is this:… S may not have thought about P at all, may have thought about Q-which is “significantly” related to P, and believes that Q; on that condition, it is conceivably true that S knows that P. (shrink)